Pharma

The Book of the Week is “Pharma– Greed, Lies, and the Poisoning of America” by Gerald Posner, published in 2020.

In 2016, the “superbug” Enterobacteriaceae turned out to be resistant to 26 different antibiotics. About half of patients who contract it, die. There are a bunch of other similar bacteria in the world. The author warned that in the future, a bacterial pandemic was on the way, for which there would be no antibiotic cure. Apparently, there can be a viral pandemic, too– one that cannot be treated with antibiotics at all.

For, antibiotics kill only bacteria, if that. Yet, in the United States, for decades, antibiotics have been prescribed to treat (mild!) viral illnesses. That is one major reason that superbugs have become a trend. And there has been an epidemic of diabetes type II. And many other adverse consequences.

Anyway, the author recounted the history of big-name drug companies, which began selling morphine to soldiers during the American Civil War. In the second half of the 1800’s, Pfizer, Squibb, Wyeth, Parke-Davis, Eli Lilly, and Burroughs-Wellcome began mostly as family proprietorships that sold highly addictive, unregulated drugs. Bayer produced heroin in 1898. The twentieth century saw Merck put cocaine in its products; other companies jumped on the cocaine bandwagon.

In 1904, the head of the United States government’s Bureau of Chemistry, Harvey Wiley, was concerned about contaminants in the nation’s food supply. Consumers were being sickened by chemicals that were supposed to retard spoilage or enhance the appeal of foods. They included, but were far from limited to: borax, salicylic acid, formaldehyde, benzoate, copper sulfate and sulfites. Trendy patent medicines were also doing harm to consumers. The word “patent” gave the impression of approval or regulation of some kind, but actually meant nothing.

Through the first third of the twentieth century, the government continued categorizing, monitoring and taxing drugs, but the pharmaceutical companies continued using trade groups and legal strategists to protect their profits. The 1930’s saw the big drug companies start research laboratories. Finally in 1938, the government established the Food and Drug Administration, and began to require extensive product-testing and labeling, and factory inspections. That same year, the Wheeler-Lea Act prohibited false advertising of drugs, except for previously manufactured barbiturates and amphetamines.

After Pearl Harbor was attacked in December 1941, America sought to manufacture penicillin in volume. For, the newly introduced antibiotic would be very helpful to the war wounded. But the drug’s fermentation process required a rare ingredient. In spring 1942, one patient who had friends in high places was cured. That largely used up the penicillin supply in the entire country. Other kinds of antibiotics were produced in the next decade, but their profitability was hampered by the bureaucratic processes of patent applications and FDA approval applications.

In the late 1940’s, Arthur Sackler and his brothers founded a family drug-company dynasty. The author revealed excessive trivia from FBI files on them and other greedy characters whose tentacles pervaded all businesses that could help sell (translation: maximize profits of) the family’s healthcare goods and services. This meant consulting, advertising, publishing, charities, public relations, database services, etc. The parties failed to disclose countless conflicts of interest.

In the early 1950’s, drug companies successfully lobbied the U.S. Patent and Trademark Office to allow drugs with strikingly similar molecular structures to be deemed different so that they could be granted separate patents. A higher number of drugs could then be rushed to market sooner, and make the most money.

In 1952, farmers fed Pfizer’s antibiotics to their animals so that they grew bigger (both Pfizer and the animals). In the mid-1950’s, Pfizer, Lederle, Squibb, Bristol and Upjohn engaged in an illegal tetracycline price-fixing scheme. They reaped hundreds of millions of dollars in earnings. The FDA chief was in Sackler’s back pocket. So when violations came to light, the FTC and FDA gave the offenders a slap on the wrist. However, senator Estes Kefauver was a thorn in their side.

Kefauver led an investigation as to why America’s drug prices were so excessively high when compared with those in other nations. In fighting back, the drug industry smeared Kefauver as a liberal pinko, claiming he had designs on forcing socialized medicine on the United States. The nineteen drugmakers under the gun gave bogus excuses. The real reason is that America’s drug prices and patents are subjected to minimal or no regulation, unlike everywhere else.

In 1956, Americans were told they were stressed, but a wonder drug called “Miltown” would help calm them down. The mild tranquilizer became a best-seller, until it was counterfeited and appeared on the black market, and its adverse side effects gave it bad publicity. Oh, well.

Then in the 1960’s came the culture-changing birth control Pill, and Valium– also called “mother’s little helper” that was marketed as a weight-loss aid. The next game-changer was thalidomide. Kefauver used the worldwide backlash against this drug to push through some drug safety and effectiveness regulation in the United States in 1963. For a change. Even so, in 1972, when the U.S. Supreme Court confirmed certain regulatory powers conferred on the FDA, drugmakers merely sought additional markets for their products on other continents.

In 1976, there was a swine flu epidemic in America. Healthcare companies were reluctant to develop a vaccine for it, fearing an orgy of litigation from victims if any harm was done. So the government unwisely agreed to foot any legal bills. Sure enough, some vaccine recipients developed cases of Guillain Barre syndrome, and neurological complications. The (taxpayer-funded) Justice Department took the hit. Other parties piled on. “The CDC had exploited ‘Washington’s panic’ to ‘increase the size of its empire and multiply its budget.’ “

Moving on, the author told the whole sordid story of the “opioid crisis” in America. In a nutshell: in May 2002, Purdue Pharma, maker and unethical marketer of OxyContin, hired Rudy Giuliani’s firm to defend it against the firestorm from its host of illegal activities. The firm collected a $3 million fee per month. Purdue collected $30 million per week from OxyContin sales. To be fair, Purdue and the Sackler family were the poster-scapegoats of the crisis. Numerous other parties aided and abetted them: other pharmaceutical companies, doctors, FDA bureaucrats, and pain management “experts” and pharmacists. The far-reaching consequences have caused a lot of trouble for society as a whole in the areas of: increased healthcare costs, criminal justice, social services, drug rehabilitation services, lost productivity and earnings, etc.

Read the book to learn an additional wealth of details and the details of wealth of the healthcare industry’s evolution into a hegemonic legal behemoth / excessive profit center, in the form of a series of cautionary tales in various topic areas– drug advertising, blood donations, biotech, epidemics, pharmacy benefit managers– that wrought major good and bad (mostly bad) cultural and regulatory changes (including the Hatch-Waxman Act and the Orphan Drug Act); plus the family battles following the sudden death of Arthur Sackler.

Klondike

The Book of the Week is “Klondike, the Alaskan Oil Boom” by Daniel Jack Chasan, published in 1971.

For decades, oil has been a political football that has caused international strife. This book recounts the story that has become a cliche: what transpired when oil was discovered in Alaska in March 1968.

Through the 1800’s, Alaska’s economy was based on fur trading (exploited by the Russians whose activities left many native Alaskans dead of disease and from weapons), canneries, sawmills, gold, and whaling (exploited by the Americans, who forced many native Alaskans to migrate or else they would starve); by the mid-1900’s, it was based on salmon, lumber, gold, copper, hunting, private prop planes, and during wartime– military bases.

In January, 1970, the author visited an Eskimo village, whose residents hunted caribou for food, lived in plywood cabins, and got around in snowmobiles. They sold masks made of caribou in tourist shops in Alaskan cities to make a living. On average, they passed away in their mid-30’s.

In 1912, the Alaskan Native Brotherhood was formed to help aboriginal Alaskans assert their legal rights. Through the decades, various tribes of natives, including the Tlingits, Haidas, Tanacross, Minto, and Inupiat had their lands grabbed by the United States federal government. Finally, in 1966, they formed a group called the Alaska Federation of Natives but it became a political front that actually separated the tribes from their lands. Different tribes had beefs with other tribes, and there were divided loyalties. In the last three years of the 1960’s, Alaska’s state government had political differences with the federal Department of the Interior.

Just a few of the actual consequences (which were ongoing, and were likely to get worse in the future, due to ongoing legal wrangling at the book’s writing) of oil discovery included:

  • Eskimos’, Indians’ and Aleuts’ ways of life were disrupted emotionally, financially and property-wise, due to the mere planning of the oil companies involved.
  • Many activities associated with the extraction of the oil were environmentally damaging to the land and air due to the construction of: a pipeline to be completed in 1972, and the flying in of temporary housing, vehicles and facilities for workers, etc. (Los Angeles would get the oil if it was ever extracted, thus decreasing oil prices and increasing its smog), and
  • Some of the parties involved with the whole extravaganza profited before a drop of oil was even extracted: lawyers, oil workers, Alaska Airlines, and Alaska’s state government– which collected revenues from lease payments, filing fees, drilling permits, etc.

There was always the incalculable potential for ecological disasters which could rear their ugly heads at any time: oil spills and earthquakes. Of course, “The Interior Department had no such trouble computing the possible benefits of the pipeline.”

Read the book to learn a wealth of additional details of why Alaska’s natives were at many disadvantages in their fight with “city hall” (hint– one was that an Alaskan senator doubled as the chair of the Senate Interior Committee, who was friendly with president Richard Nixon’s Environmental Quality Council) and which kinds of compensation, if any, to which some of them might be entitled.

See Nothing and Nobody – BONUS POST

SEE NOTHING AND NOBODY

DOWN BY THE SCHOOLYARD

sung to the tune of “See Me and Julio Down By the Schoolyard” with apologies to Paul Simon.

President Trump said reopen schools.

So did the czar of education.

When the teachers found out they began to shout,

which started the litigation.

Teachers said naw! Teachers said naw!

A lot of sick we saw.

There ought to be a law.

Florida’s gov stood his ground, said we’re not bound

to conform to the convention.

Other govs said you must open schools or we’ll legally quash your dissension.

We’ve lost our way.

Don’t know where we’re going.

We’ve lost our way.

Law takes its time. Don’t know where…

Goodbye democracy, via the scourge of Corona.

See nothing and nobody down by the schoolyard.

See nothing and nobody down by the schoolyard.

Oh oh, people are saying they’re going to take school away and have online and home education.

And when the special interest groups have total control,

we’re gonna have an airheaded nation.

We’ve lost our way.

Don’t know where we’re going.

We’ve lost our way.

Law takes its time. Don’t know where…

Goodbye democracy, via the scourge of Corona.

See nothing and nobody down by the schoolyard.

See nothing and nobody down by the schoolyard.

See nothing and nobody down by the schoolyard.

Embattled Wall

The Book of the Week is “Embattled Wall, Americans United: An Idea and a Man” by C. Stanley Lowell, published in 1966.

Separation of Church and State requires a zero-tolerance policy, lest little things open the floodgates to bigger things, one thing leads to another, and those little things eventually lead to the Spanish Inquisition, or some other theocracy as is seen in many countries in the Middle East and Central Asia.

Besides, there are other reasons for separation of Church and State:

  • Religious entities that pay no taxes have a competitive advantage if they provide goods and services the same way tax-paying capitalist entities do. This includes private education services, and
  • Citizens probably don’t want their taxes to financially assist institutions associated with a religion other than their own.

After WWII in the United States, the power of the Catholic Church was on the increase. Beginning in 1947, the Church began to aggressively request government subsidies for its parochial school system. The author wrote, “…The National Catholic Welfare Conference… [were] like professional lobbyists… actually assisting in the drafting of legislation… cajoling, promising, threatening.”

Protestants felt that money was earned through work, not subsidies, so initially, they were against public funding for their schools. Thus, when over-achieving attorney Glenn Archer founded the group, Americans United— which litigated for separation of Church and State– Protestants assisted him.

The actual full name of the organization was “Protestants and Other Americans United For Separation of Church and State” (hereinafter referred to as “AU”). Other groups that supported them included Seventh Day Adventists and Christian Scientists. Jews mostly avoided the fray, but they were offended that the group had the word “church” in its name.

The Catholics launched a smear campaign against Archer and AU. Catholic publications trotted out the usual righteously indignant accusations, “bigot, religious prejudice, Ku Klux Klan, Communist, racist,” etc. The language in Jesuit propaganda was open to multiple interpretations (among many other examples):

“Freedom of choice in education”

which, in AU’s words, translated to:

Canon Law 1374 denies freedom of choice in education to Catholic parents, ordering them to send their children to Catholic schools.” In other words, the Catholic Church strongly believes that its worshippers should follow religious law before civil law whenever there is a clash between them.

Jesuits: “Justice for children”

AU: “Subsidies for Catholic schools”

The author also described a Catholic rabble rouser: “His posture of outraged purity impressed the majority who had no understanding of the real issues in the case.”

When American president Harry Truman proposed the appointing of an ambassador to the Vatican, AU protested that this was a violation of separation of Church and State, as the leader of the Vatican (the Pope) was a worldwide religious leader. AU and a sufficient number of individual complainants helped put the kibosh on that appointment.

The State Department was peeved because it could have used the Catholic Church (which had many houses of worship around the world) to assist with espionage– er, uh, fostering friendly relationships with nations that had Catholic citizens.

In 1958, the world got a new Pope, thanks in part to votes cast by Catholic cardinals in America. AU cited 8 U.S. Code 1481 of the Immigration and Nationality Act as a reason to revoke the citizenship of those cardinals. For, any American citizen who votes in a foreign country could be stripped of his citizenship.

The Church weakly counter-argued that the Pope is primarily a religious leader, and secondarily a national leader. However, AU produced support for its own arguments in the form of a few previous legal cases of citizenship revocations, plus American government documentation that showed the Vatican to be a political entity.

During the 1960 presidential election between Richard Nixon and the Catholic John F. Kennedy, AU asked questions to determine JFK’s positions on separation of Church and State. The U.S. Supreme Court, AU and JFK were all in agreement.

A few different laws were passed through the years, that granted subsidies pursuant to state laws, in addition to ongoing student loan programs:

  • 1948, the Taft Bill
  • 1958, Defense Education Act
  • 1963, Higher Education Facilities Act (which allowed a university– even that run by a religious institution– to acquire property at a fire-sale price from the government, and then to get permission to construct campus buildings with public funds), and
  • 1965, Elementary and Secondary Education Act

During those years, in effect, federal taxpayers were financially aiding Catholic education more than that of any other religion, as 95% of religious schools were Catholic.

In the late 1950’s, Franklin County in Missouri won a great legal victory against the Catholic Church. The court ruled that, “…schools were not in fact free public schools and were not entitled to be supported by public school money or public funds.”

In a Burlington, Vermont lawsuit, AU cited the First and Fourteenth Amendments because the vague language of the Vermont Constitution regarding separation of Church and State allowed for loopholes.

Read the book to learn about the practice of “captive schools” and a wealth of additional information on the tenor of the times in connection with legal fights over public funding for religious education.

Scholar

SCHOLAR

Sung to the tune of “All Star” with apologies to Smash Mouth and John Green.

Our government exploded.

G.O.P. and Dems unloaded.

We weren’t ready for their evil campaign.

They were getting out of hand with their “Everything is banned.”

They were acting just like Abel and Cain.

Well, this is history and you can’t stop history.

If you read books then it shouldn’t be a mystery.

“You’ll get sick and die if you live for fun.”

Propaganda’s smart but it makes you dumb.

It takes books for us to see

primary sources and all details clearly.

You’ll never know if you don’t read.

It’s awareness that we need.

Hey now, you’re a scholar.

Dust your brain off. Go learn.

Hey now, ignore the noise.

Turn the show off. The worm will turn.

All that reading is go-old.

Only the narrow-minded fear all they’re told.

It’s a rough patch, and it might get rougher.

You’re troubled now.

But you don’t have to suffer.

When pundits and media push your buttons,

reading helps you ignore the panic-gluttons.

You might be surprised who takes the lead.

The voting’s getting near

so you might as well read.

Nothing’s on fire, if you’ve got books.

You’ll be calm and you’ll forget the crooks.

Hey now, you’re a scholar.

Dust your brain off. Go learn.

Hey now, ignore the noise.

Turn the show off. The worm will turn.

All that reading is go-old.

Only the narrow-minded fear all they’re told.

Hey now, you’re a scholar.

Dust your brain off. Go learn.

Hey now, ignore the noise.

Turn the show off. The worm will turn.

All that reading is go-old.

Only the narrow-minded–

Our government decided it’s forcing change;

no more sanity or freedoms in this place.

We said, “Wait. What a trauma.”

We need to vote all the incumbents out.

And we should all applaud such change.

Well, this is history and you can’t stop history.

If you read books then it shouldn’t be a mystery.

“You’ll get sick and die if you live for fun.”

Propaganda’s smart but it makes you dumb.

It takes books for us to see

primary sources and all details clearly.

You’ll never know if you don’t read.

It’s awareness that we need.

Hey now, you’re a scholar.

Dust your brain off. Go learn.

Hey now, ignore the noise.

Turn the show off. The worm will turn.

All that reading is go-old.

Only the narrow-minded fear all they’re told.

And all that reading is go-old.

Only the narrow-minded fear all they’re told.